Standard

High myopia

NFASC · rs2246661

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of High myopia compared to the general population. (GWAS Catalog, Ophthalmology 2020, PMID:32428537)

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with High myopia. (GWAS Catalog, Ophthalmology 2020, PMID:32428537)

T/T Published research associates this genotype with typical/baseline likelihood of High myopia — no copies of the reported risk allele. (GWAS Catalog, Ophthalmology 2020, PMID:32428537)

Source: GWAS Catalog, Ophthalmology 2020, PMID:32428537

Questions about rs2246661

What is rs2246661?

rs2246661 is a single position in the genome, in or near the NFASC gene. Published research associates it with high myopia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2246661 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2246661 come from?

GWAS Catalog, Ophthalmology 2020, PMID:32428537. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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