Sensitive

Mean platelet thrombocyte volume (UKB data field 30100)

near ADO · rs224091

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0224 higher (95% confidence interval 0.017-0.028); p = 4 × 10−15.

How common The T allele had a frequency of about 90% in the people studied.

Where it sits Chromosome 10, band 10q21.2 — between genes, 23.1 kb from ADO.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Mean platelet thrombocyte volume (UKB data field 30100) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mean platelet thrombocyte volume (UKB data field 30100).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mean platelet thrombocyte volume (UKB data field 30100) compared to the general population.
Source

Questions about rs224091

What is rs224091?

rs224091 is a single position in the genome, in or near the near ADO gene. Published research associates it with mean platelet thrombocyte volume (ukb data field 30100). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs224091 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs224091 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Mean platelet thrombocyte volume (UKB data field 30100) (rs224091). MyGeneLog™. https://www.mygenelog.com/variants/rs224091

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