Standard

Triglycerides

MLXIPL · rs2240466

Where this position leads

Condition: High Triglycerides

rs2240466 Condition: High Triglycerides High Triglycerides Condition rs2240466 rs2240466 MLXIPL

What the study found

Who was studied 17,100 European ancestry individuals, 715 Orcadian individuals.

The effect Each copy of the G allele shifted the measure 0.14 s.d. higher; p = 1 × 10−12.

How common The G allele had a frequency of about 87% in the people studied.

Where it sits Chromosome 7, band 7q11.23 — in the 3′ untranslated region of BAZ1B.

What each result means

A/A No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2240466

What is rs2240466?

rs2240466 is a single position in the genome, in or near the MLXIPL gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2240466 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs2240466?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2240466 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2240466 come from?

GWAS Catalog, Nat Genet 2008, PMID:19060911. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs2240466). MyGeneLog™. https://www.mygenelog.com/variants/rs2240466

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