Standard

Composite immunoglobulin trait (IgA/IgG)

TAP2 · rs2239701

What the study found

Who was studied 14,183 Icelandic ancestry individuals; replicated in 2,146 Swedish ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.08 SD units lower; p = 3 × 10−10.

How common The C allele had a frequency of about 37% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — in an intron of TAP2.

What each result means

C/C Two copies of the version the research linked to Composite immunoglobulin trait (IgA/IgG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Composite immunoglobulin trait (IgA/IgG). That is a smaller link than two copies.
T/T No copy of the version the research linked to Composite immunoglobulin trait (IgA/IgG). This is the starting point the study compared everyone against.
Source

Questions about rs2239701

What is rs2239701?

rs2239701 is a single position in the genome, in or near the TAP2 gene. Published research associates it with composite immunoglobulin trait (iga/igg). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2239701 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2239701 come from?

GWAS Catalog, Nature genetics 2017, PMID:28628107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Composite immunoglobulin trait (IgA/IgG) (rs2239701). MyGeneLog™. https://www.mygenelog.com/variants/rs2239701

← See all variants