Standard

Bicarbonate (maximum, inv-norm transformed)

SERGEF · rs2237908

What the study found

Who was studied 412,277 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0347 lower (95% confidence interval 0.03-0.04); p = 9 × 10−40.

How common The A allele had a frequency of about 61% in the people studied.

Where it sits Chromosome 11, band 11p15.1 — in an intron of SERGEF.

What each result means

A/A Two copies of the version the research linked to Bicarbonate (maximum, inv-norm transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Bicarbonate (maximum, inv-norm transformed). That is a smaller link than two copies.
G/G No copy of the version the research linked to Bicarbonate (maximum, inv-norm transformed). This is the starting point the study compared everyone against.
Source

Questions about rs2237908

What is rs2237908?

rs2237908 is a single position in the genome, in or near the SERGEF gene. Published research associates it with bicarbonate (maximum, inv-norm transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2237908 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2237908 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Bicarbonate (maximum, inv-norm transformed) (rs2237908). MyGeneLog™. https://www.mygenelog.com/variants/rs2237908

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