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Leg total mass

TFF3 · rs2236705

What the study found

Who was studied 2,294 White British ancestry female individuals.

The effect Each copy of the A allele shifted the measure 1.13 kg higher; p = 4 × 10−9.

Where it sits Chromosome 21, band 21q22.3 — in an intron of TFF3.

What each result means

A/A Two copies of the version the research linked to Leg total mass. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Leg total mass. That is a smaller link than two copies.
C/C No copy of the version the research linked to Leg total mass. This is the starting point the study compared everyone against.
Source

Questions about rs2236705

What is rs2236705?

rs2236705 is a single position in the genome, in or near the TFF3 gene. Published research associates it with leg total mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2236705 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2236705 come from?

GWAS Catalog, Frontiers in endocrinology 2021, PMID:34239500. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Leg total mass (rs2236705). MyGeneLog™. https://www.mygenelog.com/variants/rs2236705

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