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Who was studied 56 Greater Middle Eastern ancestry cases, 5 unknown ancestry cases, 36 Greater Middle Eastern ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 5 × 10−11.
How common The T allele had a frequency of about 28% in the people studied.
Where it sits Chromosome 20, band 20p12.1 — a missense change in KIF16B.
What each result means
C/CNo copy of the version the research linked to Hodgkin's lymphoma. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Hodgkin's lymphoma. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Hodgkin's lymphoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
International journal of laboratory hematology · 2021 · PMID 34216518
Questions about rs2236145
What is rs2236145?
rs2236145 is a single position in the genome, in or near the KIF16B gene. Published research associates it with hodgkin's lymphoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2236145 linked to?
On MyGeneLog this position is linked to Hodgkin Lymphoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs2236145 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2236145 come from?
GWAS Catalog, International journal of laboratory hematology 2021, PMID:34216518. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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