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MSLN plasma levels

near MSLN · rs2235503

What the study found

Who was studied 400 French ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.335 nM higher (95% confidence interval 0.26-0.41); p = 9 × 10−18.

Where it sits Chromosome 16, band 16p13.3 — between genes, 0.1 kb from MSLN.

What each result means

A/A No copy of the version the research linked to MSLN plasma levels. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to MSLN plasma levels. That is a smaller link than two copies.
C/C Two copies of the version the research linked to MSLN plasma levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2235503

What is rs2235503?

rs2235503 is a single position in the genome, in or near the near MSLN gene. Published research associates it with msln plasma levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2235503 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2235503 come from?

GWAS Catalog, Genome medicine 2022, PMID:35264221. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

MSLN plasma levels (rs2235503). MyGeneLog™. https://www.mygenelog.com/variants/rs2235503

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