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Who was studied 1,972 East Asian ancestry cases, 12,236 East Asian ancestry controls.
The effect
Each copy of the G allele carried 0.74 times the odds of IgG4-related disease (95% confidence interval 0.6679-0.8209); p = 1 × 10−8.
Where it sits Chromosome 6, band 6p21.33 — between genes, 0.6 kb from C6orf15.
What each result means
A/ANo copy of the version the research linked to IgG4-related disease. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to IgG4-related disease. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to IgG4-related disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Annals of the rheumatic diseases · 2026 · PMID 41298177
Questions about rs2233964
What is rs2233964?
rs2233964 is a single position in the genome, in or near the near C6orf15 gene. Published research associates it with igg4-related disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2233964 linked to?
On MyGeneLog this position is linked to IgG4-Related Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs2233964 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2233964 come from?
GWAS Catalog, Annals of the rheumatic diseases 2026, PMID:41298177. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 27214123113Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others13Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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