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Waist-to-hip ratio adjusted for BMI

C6orf15 · rs2233956

What the study found

Who was studied 186,825 British ancestry men.

The effect Each copy of the C allele shifted the measure 0.0328 lower (95% confidence interval 0.025-0.04); p = 3 × 10−18.

Where it sits Chromosome 6, band 6p21.33 — between genes, 0.9 kb from C6orf15.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Waist-to-hip ratio adjusted for BMI compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Waist-to-hip ratio adjusted for BMI.
T/T Published research associates this genotype with typical/baseline likelihood of Waist-to-hip ratio adjusted for BMI — no copies of the reported risk allele.
Source

Questions about rs2233956

What is rs2233956?

rs2233956 is a single position in the genome, in or near the C6orf15 gene. Published research associates it with waist-to-hip ratio adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2233956 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2233956 come from?

GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist-to-hip ratio adjusted for BMI (rs2233956). MyGeneLog™. https://www.mygenelog.com/variants/rs2233956

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