0 18162315Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot6Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others5Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 313,125 European ancestry individuals, 5,568 African ancestry individuals, 6,693 South Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0792 higher (95% confidence interval 0.071-0.087); p = 1 × 10−81.
Where it sits Chromosome 2, band 2q31.1 — a missense change in SPC25.
What ClinVar records
ClassificationBenign for G6PC2-related disorder; criteria provided, single submitter (1 of 4 stars, 2 submitters), last evaluated 2024-11-26.
ClinVar record 3059418NM_021176.3(G6PC2):c.1025C>G (p.Ser342Cys)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CNo copy of the version the research linked to Blood glucose levels. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Blood glucose levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Blood glucose levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs2232328
What is rs2232328?
rs2232328 is a single position in the genome, in or near the SPC25 gene. Published research associates it with blood glucose levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2232328 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs2232328 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2232328 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 18162315Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot6Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others5Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.