A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gout compared to the general population. (GWAS Catalog, Ann Rheum Dis 2021, PMID:33832965)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gout. (GWAS Catalog, Ann Rheum Dis 2021, PMID:33832965)
G/GPublished research associates this genotype with typical/baseline likelihood of Gout — no copies of the reported risk allele. (GWAS Catalog, Ann Rheum Dis 2021, PMID:33832965)
Source: GWAS Catalog, Ann Rheum Dis 2021, PMID:33832965
Questions about rs2229357
What is rs2229357?
rs2229357 is a single position in the genome, in or near the INHBC gene. Published research associates it with gout. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2229357 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs2229357 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2229357 come from?
GWAS Catalog, Ann Rheum Dis 2021, PMID:33832965. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.