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Asthma

ADORA1 · rs2228079

Where this position leads

Condition: Asthma

rs2228079 Condition: Asthma Asthma Condition rs2228079 rs2228079 ADORA1

What the study found

Who was studied 16,247 European ancestry cases, 346,486 European ancestry controls, 52,942 cases, 355,713 controls.

The effect Each copy of the T allele carried 1.05 times the odds of Asthma (95% confidence interval 1.03-1.06); p = 8 × 10−12.

How common The T allele had a frequency of about 67% in the people studied.

Where it sits Chromosome 1, band 1q32.1 — a synonymous change in ADORA1.

What each result means

G/G No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Asthma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2228079

What is rs2228079?

rs2228079 is a single position in the genome, in or near the ADORA1 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2228079 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs2228079 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2228079 come from?

GWAS Catalog, Nature communications 2020, PMID:31959851. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs2228079). MyGeneLog™. https://www.mygenelog.com/variants/rs2228079

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