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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 482 African American child cases, 2,048 African American controls.
The effect
Each copy of the G allele carried 2.14 times the odds of Pneumonia (95% confidence interval 1.78-2.57); p = 5 × 10−16.
Where it sits Chromosome 11, band 11p15.4 — in an intron of HBG2.
What each result means
G/GTwo copies of the version the research linked to Pneumonia. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Pneumonia. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Pneumonia. This is the starting point the study compared everyone against.
rs2226952 is a single position in the genome, in or near the HBG2 gene. Published research associates it with pneumonia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2226952 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2226952 come from?
GWAS Catalog, HGG advances 2025, PMID:39444160. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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