Male puberty timing (late vs. average onset facial hair)
KANSL1 · rs2222746
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 26,066 European ancestry late onset individuals, 161,175 European ancestry average onset individuals.
The effect
Each copy of the T allele shifted the measure 0.0165 years higher (95% confidence interval 0.014-0.019); p = 2 × 10−30.
Where it sits Chromosome 17, band 17q21.31 — in an intron of KANSL1.
What each result means
G/GNo copy of the version the research linked to Male puberty timing (late vs. average onset facial hair). This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Male puberty timing (late vs. average onset facial hair). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Male puberty timing (late vs. average onset facial hair). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2020 · PMID 32210231 · open access
Questions about rs2222746
What is rs2222746?
rs2222746 is a single position in the genome, in or near the KANSL1 gene. Published research associates it with male puberty timing (late vs. average onset facial hair). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2222746 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2222746 come from?
GWAS Catalog, Nature communications 2020, PMID:32210231. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Male puberty timing (late vs. average onset facial hair) (rs2222746). MyGeneLog™. https://www.mygenelog.com/variants/rs2222746