Standard

Highest math class taken (MTAG)

CNTNAP4 · rs2221534

Where this position leads

Condition: Educational Attainment

rs2221534 Condition: Educational Attainment Educational Attainment Condition rs2221534 rs2221534 CNTNAP4

What the study found

Who was studied 811,539 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0116 higher (95% confidence interval 0.0083-0.0149); p = 3 × 10−12.

How common The A allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 16, band 16q23.1 — in an intron of CNTNAP4.

What each result means

A/A Two copies of the version the research linked to Highest math class taken (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Highest math class taken (MTAG). That is a smaller link than two copies.
C/C No copy of the version the research linked to Highest math class taken (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs2221534

What is rs2221534?

rs2221534 is a single position in the genome, in or near the CNTNAP4 gene. Published research associates it with highest math class taken (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2221534 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs2221534 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2221534 come from?

GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Highest math class taken (MTAG) (rs2221534). MyGeneLog™. https://www.mygenelog.com/variants/rs2221534

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