Standard

Total bilirubin levels

near MAFB · rs2207132

Where this position leads

Condition: Gout

rs2207132 Condition: Gout Gout Condition rs2207132 rs2207132 near MAFB

What the study found

Who was studied 341,077 European ancestry individuals, 5,978 African ancestry individuals, 7,313 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0407 lower (95% confidence interval 0.028-0.054); p = 2 × 10−9.

Where it sits Chromosome 20, band 20q12 — between genes, 46.1 kb from LOC105372618.

What each result means

A/A Two copies of the version the research linked to Total bilirubin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Total bilirubin levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Total bilirubin levels. This is the starting point the study compared everyone against.
Source

Questions about rs2207132

What is rs2207132?

rs2207132 is a single position in the genome, in or near the near MAFB gene. Published research associates it with total bilirubin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2207132 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs2207132 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2207132 come from?

GWAS Catalog, Nat Genet 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total bilirubin levels (rs2207132). MyGeneLog™. https://www.mygenelog.com/variants/rs2207132

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