Standard

Daytime nap

PAM · rs2195272

Where this position leads

Condition: Sleep and Circadian Rhythm

rs2195272 Condition: Sleep and Circadian Rhythm Sleep and Circadian Rhythm Condition rs2195272 rs2195272 PAM

What the study found

Who was studied 452,633 European ancestry individuals; replicated in 541,333 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.007 higher (95% confidence interval 0.0052-0.0088); p = 3 × 10−14.

Where it sits Chromosome 5, band 5q21.1 — in an intron of PAM.

What each result means

G/G No copy of the version the research linked to Daytime nap. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Daytime nap. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Daytime nap. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2195272

What is rs2195272?

rs2195272 is a single position in the genome, in or near the PAM gene. Published research associates it with daytime nap. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2195272 linked to?

On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.

Does having rs2195272 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2195272 come from?

GWAS Catalog, Nat Commun 2021, PMID:33568662. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Daytime nap (rs2195272). MyGeneLog™. https://www.mygenelog.com/variants/rs2195272

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