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Volume of right lateral nucleus

near IGF1 · rs2195243

What the study found

Who was studied 35,474 European ancestry individuals, 6,923 East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0591 lower (95% confidence interval 0.046-0.073); p = 6 × 10−18.

Where it sits Chromosome 12, band 12q23.2 — between genes, 47.5 kb from IGF1.

What each result means

C/C Two copies of the version the research linked to Volume of right lateral nucleus. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Volume of right lateral nucleus. That is a smaller link than two copies.
G/G No copy of the version the research linked to Volume of right lateral nucleus. This is the starting point the study compared everyone against.
Source

Questions about rs2195243

What is rs2195243?

rs2195243 is a single position in the genome, in or near the near IGF1 gene. Published research associates it with volume of right lateral nucleus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2195243 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2195243 come from?

GWAS Catalog, Nature genetics 2025, PMID:40097784. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Volume of right lateral nucleus (rs2195243). MyGeneLog™. https://www.mygenelog.com/variants/rs2195243

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