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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 252,287 European ancestry cases, 150,908 European ancestry controls; replicated in 120,478 European ancestry cases, 127,622 European ancestry controls.
The effect
The reported allele is C; the catalogue records no effect size
; p = 3 × 10−15.
How common The C allele had a frequency of about 74% in the people studied.
Where it sits Chromosome 16, band 16q22.2 — in an intron of LINC01572.
What each result means
C/CTwo copies of the version the research linked to Morning person. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Morning person. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Morning person. This is the starting point the study compared everyone against.
Nature communications · 2019 · PMID 30696823 · open access
Questions about rs2194316
What is rs2194316?
rs2194316 is a single position in the genome, in or near the PMFBP1 gene. Published research associates it with morning person. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2194316 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2194316 come from?
GWAS Catalog, Nature communications 2019, PMID:30696823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Morning person (rs2194316). MyGeneLog™. https://www.mygenelog.com/variants/rs2194316