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Interleukin-1 Receptor accessory protein levels

IL1RAP · rs2193873

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.334 higher (95% confidence interval 0.26-0.41); p = 2 × 10⁻¹⁷.

Where it sits Chromosome 3, band 3q28 — in an intron of IL1RAP.

What each result means

A/A No copy of the version the research linked to Interleukin-1 Receptor accessory protein levels. This is the starting point the study compared everyone against.

A/G One copy of the version the research linked to Interleukin-1 Receptor accessory protein levels. That is a smaller link than two copies.

G/G Two copies of the version the research linked to Interleukin-1 Receptor accessory protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Connecting genetic risk to disease end points through the human blood plasma proteome

Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M

and 12 more — show all

Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J

Nature communications · 2017 · PMID 28240269 · open access

Questions about rs2193873

What is rs2193873?

rs2193873 is a single position in the genome, in or near the IL1RAP gene. Published research associates it with interleukin-1 receptor accessory protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2193873 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2193873 come from?

GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Interleukin-1 Receptor accessory protein levels (rs2193873). MyGeneLog™. https://www.mygenelog.com/variants/rs2193873

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