0 342228133211Reads by AI crawlersClaude2ChatGPT2Google · Gemini2Perplexity0Meta AI8Microsoft · Copilot1Amazon3Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others11Total34Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 34,930 East Asian ancestry individuals, 187,167 European ancestry individuals; replicated in 8,741 Chinese ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.061 higher (95% confidence interval 0.039-0.083); p = 2 × 10−8.
How common The T allele had a frequency of about 82% in the people studied.
Where it sits Chromosome 12, band 12q24.11 — in an intron of MYL2.
What each result means
C/CNo copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs2188380 is a single position in the genome, in or near the MYL2 gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2188380 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs2188380 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2188380 come from?
GWAS Catalog, Hum Mol Genet 2017, PMID:28334899. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 342228133211Reads by AI crawlersClaude2ChatGPT2Google · Gemini2Perplexity0Meta AI8Microsoft · Copilot1Amazon3Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others11Total34Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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