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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 390,964 European ancestry individuals; replicated in 105,030 East Asian ancestry individuals.
The effect
Each copy of the T allele shifted the measure 17.4 z-score higher; p = 1 × 10−67.
How common The T allele had a frequency of about 33% in the people studied.
Where it sits Chromosome 9, band 9q31.1 — between genes, 7.2 kb from ALDOB.
What each result means
A/ANo copy of the version the research linked to Serum alkaline phosphatase levels. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Serum alkaline phosphatase levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Serum alkaline phosphatase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2021 · PMID 33547301 · open access
Questions about rs2183745
What is rs2183745?
rs2183745 is a single position in the genome, in or near the ALDOB gene. Published research associates it with serum alkaline phosphatase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2183745 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2183745 come from?
GWAS Catalog, Nature communications 2021, PMID:33547301. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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