Standard

Neutrophil count

near LINC02260 · rs218252

What the study found

Who was studied 234,802 European ancestry individuals; replicated in 100,556 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−11.

How common The G allele had a frequency of about 78% in the people studied.

Where it sits Chromosome 4, band 4q12 — between genes, 70.2 kb from LINC02260.

What each result means

G/G Two copies of the version the research linked to Neutrophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Neutrophil count. That is a smaller link than two copies.
T/T No copy of the version the research linked to Neutrophil count. This is the starting point the study compared everyone against.
Source

Questions about rs218252

What is rs218252?

rs218252 is a single position in the genome, in or near the near LINC02260 gene. Published research associates it with neutrophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs218252 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs218252 come from?

GWAS Catalog, American journal of human genetics 2021, PMID:34469753. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Neutrophil count (rs218252). MyGeneLog™. https://www.mygenelog.com/variants/rs218252

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