0 35111222116Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot12Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others16Total35Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 12,093 African American or Afro-Caribbean cases, 105,134 African American or Afro-Caribbean controls, 5,688 Hispanic or Latin American cases, 52,071 Hispanic or Latin American controls, 609 East Asian ancestry cases, 6,004 East Asian ancestry controls, 36,823 European ancestry cases, 398,278 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0486 higher (95% confidence interval 0.034-0.063); p = 2 × 10−11.
How common The T allele had a frequency of about 60% in the people studied.
Where it sits Chromosome 6, band 6q15 — in an intron of BACH2.
What each result means
C/CNo copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Asthma. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs2174281
What is rs2174281?
rs2174281 is a single position in the genome, in or near the BACH2 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2174281 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs2174281 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2174281 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 35111222116Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot12Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others16Total35Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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