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Body mass index

IPO9 · rs2172935

Where this position leads

Conditions: Childhood Body Mass Index, Obesity and Body Weight, Waist-to-Hip Ratio (Body Fat Distribution)

rs2172935 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition Condition: Waist-to-Hip Ratio (Body Fat Distribution) Waist-to-Hip Ratio (Body Fat Distri… Condition rs2172935 rs2172935 IPO9

What the study found

Who was studied 374,756 European ancestry male individuals.

The effect Each copy of the T allele shifted the measure 0.0235 higher (95% confidence interval 0.02-0.027); p = 6 × 10−39.

How common The T allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 1, band 1q32.1 — in an intron of IPO9.

What each result means

C/C No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2172935

What is rs2172935?

rs2172935 is a single position in the genome, in or near the IPO9 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2172935 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index, Obesity and Body Weight, Waist-to-Hip Ratio (Body Fat Distribution). The research behind each link, and its sources, are set out on that condition page.

Does having rs2172935 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2172935 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs2172935). MyGeneLog™. https://www.mygenelog.com/variants/rs2172935

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