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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 35,928 European ancestry individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 1 × 10−16.
Where it sits Chromosome 3, band 3p25.1 — between genes, 51.9 kb from LSM3.
What each result means
C/CNo copy of the version the research linked to Right ventricular end systolic volume. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Right ventricular end systolic volume. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Right ventricular end systolic volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science advances · 2023 · PMID 37126556 · open access
Questions about rs2170454
What is rs2170454?
rs2170454 is a single position in the genome, in or near the near LSM3 gene. Published research associates it with right ventricular end systolic volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2170454 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2170454 come from?
GWAS Catalog, Science advances 2023, PMID:37126556. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Right ventricular end systolic volume (rs2170454). MyGeneLog™. https://www.mygenelog.com/variants/rs2170454