2 303211712310Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others10Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied up 62,166 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.083 s.d. higher (95% confidence interval 0.063-0.103); p = 3 × 10−16.
How common The G allele had a frequency of about 89% in the people studied.
Where it sits Chromosome 8, band 8p23.1 — in an intron of PPP1R3B-DT.
What each result means
A/ANo copy of the version the research linked to LDL cholesterol. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to LDL cholesterol. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to LDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs2169387 is a single position in the genome, in or near the PPP1R3B gene. Published research associates it with ldl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2169387 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs2169387 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2169387 come from?
GWAS Catalog, Nat Genet 2015, PMID:25961943. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 303211712310Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others10Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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