Standard

Height

GLI2 · rs2166898

Where this position leads

Condition: Height

rs2166898 Condition: Height Height Condition rs2166898 rs2166898 GLI2

What the study found

Who was studied 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0325 lower (95% confidence interval 0.031-0.034); p = 2 × 10−286.

How common The A allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 2, band 2q14.2 — in an intron of GLI2.

What each result means

A/A Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Height. That is a smaller link than two copies.
G/G No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Questions about rs2166898

What is rs2166898?

rs2166898 is a single position in the genome, in or near the GLI2 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2166898 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs2166898 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2166898 come from?

GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs2166898). MyGeneLog™. https://www.mygenelog.com/variants/rs2166898

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