Standard
Allergic rhinitis
PLCL1 · rs2164068
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Allergic rhinitis — no copies of the reported risk allele.
A/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Allergic rhinitis.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Allergic rhinitis compared to the general population.
Source
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis
Waage J,
Standl M,
Curtin JA,
Jessen LE,
Thorsen J,
Tian C,
Schoettler N,
Flores C,
Abdellaoui A,
Ahluwalia TS,
Alves AC,
Amaral AFS
and 76 more — show all
Antó JM,
Arnold A,
Barreto-Luis A,
Baurecht H,
van Beijsterveldt CEM,
Bleecker ER,
Bonàs-Guarch S,
Boomsma DI,
Brix S,
Bunyavanich S,
Burchard EG,
Chen Z,
Curjuric I,
Custovic A,
den Dekker HT,
Dharmage SC,
Dmitrieva J,
Duijts L,
Ege MJ,
Gauderman WJ,
Georges M,
Gieger C,
Gilliland F,
Granell R,
Gui H,
Hansen T,
Heinrich J,
Henderson J,
Hernandez-Pacheco N,
Holt P,
Imboden M,
Jaddoe VWV,
Jarvelin MR,
Jarvis DL,
Jensen KK,
Jónsdóttir I,
Kabesch M,
Kaprio J,
Kumar A,
Lee YA,
Levin AM,
Li X,
Lorenzo-Diaz F,
Melén E,
Mercader JM,
Meyers DA,
Myers R,
Nicolae DL,
Nohr EA,
Palviainen T,
Paternoster L,
Pennell CE,
Pershagen G,
Pino-Yanes M,
Probst-Hensch NM,
Rüschendorf F,
Simpson A,
Stefansson K,
Sunyer J,
Sveinbjornsson G,
Thiering E,
Thompson PJ,
Torrent M,
Torrents D,
Tung JY,
Wang CA,
Weidinger S,
Weiss S,
Willemsen G,
Williams LK,
Ober C,
Hinds DA,
Ferreira MA,
Bisgaard H,
Strachan DP,
Bønnelykke K
Nature genetics · 2018 · PMID 30013184
Questions about rs2164068
What is rs2164068?
rs2164068 is a single position in the genome, in or near the PLCL1 gene. Published research associates it with allergic rhinitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2164068 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2164068 come from?
GWAS Catalog, Nat Genet 2018, PMID:30013184. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants