Standard

Diastolic blood pressure

near MTND1P22 · rs2138741

Where this position leads

Condition: Blood Pressure

rs2138741 Condition: Blood Pressure Blood Pressure Condition rs2138741 rs2138741 near MTND1P22

What the study found

Who was studied 153,950 Korean ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0274 lower (95% confidence interval 0.019-0.036); p = 4 × 10−11.

How common The G allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 4, band 4q32.1 — between genes, 70.6 kb from MTND1P22.

What each result means

G/G Two copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
T/T No copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs2138741

What is rs2138741?

rs2138741 is a single position in the genome, in or near the near MTND1P22 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2138741 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs2138741 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2138741 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diastolic blood pressure (rs2138741). MyGeneLog™. https://www.mygenelog.com/variants/rs2138741

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