ANKS1B · rs2133896
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 521 Han Chinese ancestry alcohol dependence cases, 1,026 Han Chinese ancestry heroin dependence cases, 1,749 Han Chinese ancestry methamphetamine dependence cases, 2,859 Han Chinese ancestry controls; replicated in 146 Han Chinese ancestry alcohol dependence cases, 1,045 Han Chinese ancestry heroin dependence cases, 763 Han Chinese ancestry methamphetamine dependence cases, 1,904 Han Chinese ancestry controls.
The effect Each copy of the T allele shifted the measure 0.104 higher (95% confidence interval 0.069-0.139); p = 4 × 10−9.
How common The T allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 12, band 12q23.1 — in an intron of ANKS1B.
rs2133896 is a single position in the genome, in or near the ANKS1B gene. Published research associates it with alcohol dependence or heroin dependence or methamphetamine dependence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Molecular psychiatry 2021, PMID:31462767. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Alcohol dependence or heroin dependence or methamphetamine dependence (rs2133896). MyGeneLog™. https://www.mygenelog.com/variants/rs2133896