A/APublished research associates this genotype with typical/baseline likelihood of Non-small cell lung cancer — no copies of the reported risk allele. (GWAS Catalog, Hum Mol Genet 2010, PMID:20876614)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Non-small cell lung cancer. (GWAS Catalog, Hum Mol Genet 2010, PMID:20876614)
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Non-small cell lung cancer compared to the general population. (GWAS Catalog, Hum Mol Genet 2010, PMID:20876614)
rs2131877 is a single position in the genome, in or near the C3orf21 gene. Published research associates it with non-small cell lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2131877 linked to?
On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs2131877 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2131877 come from?
GWAS Catalog, Hum Mol Genet 2010, PMID:20876614. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.