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Who was studied 9,266 European ancestry cases, 15,574 European ancestry controls; replicated in 4,329 European ancestry cases, 9,543 European ancestry controls.
The effect
Each copy of the A allele carried 2.12 times the odds of Type 1 diabetes (95% confidence interval 1.71-2.63); p = 8 × 10−12.
How common The A allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 21, band 21q21.1 — in an intron of LINC00320.
What each result means
A/ATwo copies of the version the research linked to Type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Type 1 diabetes. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Type 1 diabetes. This is the starting point the study compared everyone against.
rs2128344 is a single position in the genome, in or near the LINC00320 gene. Published research associates it with type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2128344 linked to?
On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs2128344 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2128344 come from?
GWAS Catalog, Diabetes 2020, PMID:32005708. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 1 diabetes (rs2128344). MyGeneLog™. https://www.mygenelog.com/variants/rs2128344