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Who was studied 405,540 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.00847 higher (95% confidence interval 0.0059-0.011); p = 1 × 10−10.
How common The A allele had a frequency of about 60% in the people studied.
Where it sits Chromosome 1, band 1p34.3 — in an intron of INPP5B.
What each result means
A/ATwo copies of the version the research linked to Height (baseline). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Height (baseline). That is a smaller link than two copies.
C/CNo copy of the version the research linked to Height (baseline). This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40374629 · open access
Questions about rs2127647
What is rs2127647?
rs2127647 is a single position in the genome, in or near the INPP5B gene. Published research associates it with height (baseline). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2127647 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs2127647 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2127647 come from?
GWAS Catalog, Nature communications 2025, PMID:40374629. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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