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Subcutaneous adipose tissue

GSDMB · rs2123685

What the study found

Who was studied 7,399 European ancestry women, 2,163 African American women.

The effect Each copy of the T allele shifted the measure 5.52 z-score higher; p = 3 × 10−8.

How common The T allele had a frequency of about 94% in the people studied.

Where it sits Chromosome 17, band 17q21.1 — between genes, 7 kb from GSDMB.

What each result means

C/C No copy of the version the research linked to Subcutaneous adipose tissue. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Subcutaneous adipose tissue. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Subcutaneous adipose tissue. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2123685

What is rs2123685?

rs2123685 is a single position in the genome, in or near the GSDMB gene. Published research associates it with subcutaneous adipose tissue. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2123685 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2123685 come from?

GWAS Catalog, Nat Genet 2016, PMID:27918534. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Subcutaneous adipose tissue (rs2123685). MyGeneLog™. https://www.mygenelog.com/variants/rs2123685

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