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Immunoglobulin lambda-like polypeptide 1 levels (IGLL1.6485.59.3)

near SLC7A10 · rs2081048

What the study found

Who was studied 3,301 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.19 higher (95% confidence interval 0.13-0.25); p = 1 × 10−12.

How common The C allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 19, band 19q13.11 — between genes, 36.4 kb from SLC7A10.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Immunoglobulin lambda-like polypeptide 1 levels (IGLL1.6485.59.3) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Immunoglobulin lambda-like polypeptide 1 levels (IGLL1.6485.59.3).
T/T Published research associates this genotype with typical/baseline likelihood of Immunoglobulin lambda-like polypeptide 1 levels (IGLL1.6485.59.3) — no copies of the reported risk allele.
Source

Questions about rs2081048

What is rs2081048?

rs2081048 is a single position in the genome, in or near the near SLC7A10 gene. Published research associates it with immunoglobulin lambda-like polypeptide 1 levels (igll1.6485.59.3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2081048 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2081048 come from?

GWAS Catalog, Nature 2018, PMID:29875488. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Immunoglobulin lambda-like polypeptide 1 levels (IGLL1.6485.59.3) (rs2081048). MyGeneLog™. https://www.mygenelog.com/variants/rs2081048

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