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Who was studied 381,152 European female individuals.
The effect
Each copy of the T allele shifted the measure 0.0141 lower (95% confidence interval 0.0098-0.0184); p = 6 × 10−11.
How common The T allele had a frequency of about 23% in the people studied.
Where it sits Chromosome 1, band 1p13.2 — in an intron of INKA2.
What each result means
C/CNo copy of the version the research linked to Waist-hip ratio. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Waist-hip ratio. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Waist-hip ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Human molecular genetics · 2019 · PMID 30239722 · open access
Questions about rs2076586
What is rs2076586?
rs2076586 is a single position in the genome, in or near the INKA2 gene. Published research associates it with waist-hip ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2076586 linked to?
On MyGeneLog this position is linked to Waist-to-Hip Ratio (Body Fat Distribution). The research behind each link, and its sources, are set out on that condition page.
Does having rs2076586 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2076586 come from?
GWAS Catalog, Human molecular genetics 2019, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Waist-hip ratio (rs2076586). MyGeneLog™. https://www.mygenelog.com/variants/rs2076586