Sensitive

Chronotype and breast cancer

CYP51A1 · rs2075881

Where this position leads

Condition: Breast Cancer

rs2075881 Condition: Breast Cancer Breast Cancer Condition rs2075881 rs2075881 CYP51A1

What the study found

Who was studied 133,384 European ancestry breast cancer cases, 113,789 European ancestry controls, 449,734 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 1 × 10−11.

Where it sits Chromosome 7, band 7q21.2 — in an intron of CYP51A1.

What each result means

C/C No copy of the version the research linked to Chronotype and breast cancer. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Chronotype and breast cancer. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Chronotype and breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2075881

What is rs2075881?

rs2075881 is a single position in the genome, in or near the CYP51A1 gene. Published research associates it with chronotype and breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2075881 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs2075881 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2075881 come from?

GWAS Catalog, Journal of sleep research 2024, PMID:37380357. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Chronotype and breast cancer (rs2075881). MyGeneLog™. https://www.mygenelog.com/variants/rs2075881

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