Standard

Waist circumference

LHX2 · rs2075064

Where this position leads

Condition: Waist Circumference

rs2075064 Condition: Waist Circumference Waist Circumference Condition rs2075064 rs2075064 LHX2

What the study found

Who was studied Up to 23,564 African American individuals; replicated in Up to 10,027 African American individuals.

The effect Each copy of the T allele shifted the measure 0.07 lower (95% confidence interval 0.05-0.09); p = 2 × 10−8.

How common The T allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 9, band 9q33.3 — in an intron of LHX2.

What each result means

C/C No copy of the version the research linked to Waist circumference. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Waist circumference. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Waist circumference. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2075064

What is rs2075064?

rs2075064 is a single position in the genome, in or near the LHX2 gene. Published research associates it with waist circumference. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2075064 linked to?

On MyGeneLog this position is linked to Waist Circumference. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs2075064?

Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2075064 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2075064 come from?

GWAS Catalog, PLoS Genet 2013, PMID:23966867. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Waist circumference (rs2075064). MyGeneLog™. https://www.mygenelog.com/variants/rs2075064

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