Standard

IgA nephropathy

ACCS · rs2074038

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of IgA nephropathy — no copies of the reported risk allele.

G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with IgA nephropathy.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of IgA nephropathy compared to the general population.

Source

Identification of new susceptibility loci for IgA nephropathy in Han Chinese

Li M, Foo JN, Wang JQ, Low HQ, Tang XQ, Toh KY, Yin PR, Khor CC, Goh YF, Irwan ID, Xu RC, Andiappan AK

and 29 more — show all

Bei JX, Rotzschke O, Chen MH, Cheng CY, Sun LD, Jiang GR, Wong TY, Lin HL, Aung T, Liao YH, Saw SM, Ye K, Ebstein RP, Chen QK, Shi W, Chew SH, Chen J, Zhang FR, Li SP, Xu G, Shyong Tai E, Wang L, Chen N, Zhang XJ, Zeng YX, Zhang H, Liu ZH, Yu XQ, Liu JJ

Nature communications · 2015 · PMID 26028593 · open access

What people read about alongside this

Infection and immunity1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2074038

What is rs2074038?

rs2074038 is a single position in the genome, in or near the ACCS gene. Published research associates it with iga nephropathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs2074038?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2074038 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2074038 come from?

GWAS Catalog, Nat Commun 2015, PMID:26028593. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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