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Phosphatidylcholines (18:2/20:2) (Model 2)

FADS2 · rs2072114

What the study found

Who was studied 6,201 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.316 lower; p = 3 × 10−32.

Where it sits Chromosome 11, band 11q12.2 — in an intron of FADS2.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Phosphatidylcholines (18:2/20:2) (Model 2) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Phosphatidylcholines (18:2/20:2) (Model 2).
G/G Published research associates this genotype with typical/baseline likelihood of Phosphatidylcholines (18:2/20:2) (Model 2) — no copies of the reported risk allele.
Source

Questions about rs2072114

What is rs2072114?

rs2072114 is a single position in the genome, in or near the FADS2 gene. Published research associates it with phosphatidylcholines (18:2/20:2) (model 2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2072114 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2072114 come from?

GWAS Catalog, Nature communications 2026, PMID:42069741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Phosphatidylcholines (18:2/20:2) (Model 2) (rs2072114). MyGeneLog™. https://www.mygenelog.com/variants/rs2072114

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