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Peptidyl-prolyl cis-trans isomerase D levels

PPID · rs2070631

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 1.26 lower (95% confidence interval 1.19-1.33); p = 5 × 10−270.

How common The A allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 4, band 4q32.1 — a missense change in PPID.

What each result means

A/A Two copies of the version the research linked to Peptidyl-prolyl cis-trans isomerase D levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Peptidyl-prolyl cis-trans isomerase D levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Peptidyl-prolyl cis-trans isomerase D levels. This is the starting point the study compared everyone against.
Source

Questions about rs2070631

What is rs2070631?

rs2070631 is a single position in the genome, in or near the PPID gene. Published research associates it with peptidyl-prolyl cis-trans isomerase d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2070631 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2070631 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Peptidyl-prolyl cis-trans isomerase D levels (rs2070631). MyGeneLog™. https://www.mygenelog.com/variants/rs2070631

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