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Blood N-acetylkynurenine (2) levels

ACTG2 · rs2070581

What the study found

Who was studied 4,759 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.428 higher (95% confidence interval 0.31-0.54); p = 2 × 10−13.

How common The G allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 2, band 2p13.1 — inside ACTG2.

What each result means

A/A No copy of the version the research linked to Blood N-acetylkynurenine (2) levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Blood N-acetylkynurenine (2) levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Blood N-acetylkynurenine (2) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2070581

What is rs2070581?

rs2070581 is a single position in the genome, in or near the ACTG2 gene. Published research associates it with blood n-acetylkynurenine (2) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2070581 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2070581 come from?

GWAS Catalog, Genome biology 2026, PMID:42426908. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blood N-acetylkynurenine (2) levels (rs2070581). MyGeneLog™. https://www.mygenelog.com/variants/rs2070581

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