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Who was studied 1,816 European ancestry cases, 7,877 European ancestry controls; replicated in 1,281 European ancestry cases, 3,218 European ancestry controls.
The effect
Each copy of the A allele carried 1.59 times the odds of Hodgkin's lymphoma (95% confidence interval 1.39–1.82); p = 2 × 10−11.
How common The A allele had a frequency of about 7% in the people studied.
Where it sits Chromosome 5, band 5q31.1 — inside TH2LCRR.
What each result means
A/ATwo copies of the version the research linked to Hodgkin's lymphoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Hodgkin's lymphoma. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Hodgkin's lymphoma. This is the starting point the study compared everyone against.
Nature communications · 2014 · PMID 24920014 · open access
Questions about rs2069757
What is rs2069757?
rs2069757 is a single position in the genome, in or near the IL13 gene. Published research associates it with hodgkin's lymphoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2069757 linked to?
On MyGeneLog this position is linked to Hodgkin Lymphoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs2069757 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2069757 come from?
GWAS Catalog, Nat Commun 2014, PMID:24920014. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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