Standard
Hodgkin's lymphoma
IL13 · rs2069757
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hodgkin's lymphoma compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hodgkin's lymphoma.
G/G
Published research associates this genotype with typical/baseline likelihood of Hodgkin's lymphoma — no copies of the reported risk allele.
Source
A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus
Cozen W,
Timofeeva MN,
Li D,
Diepstra A,
Hazelett D,
Delahaye-Sourdeix M,
Edlund CK,
Franke L,
Rostgaard K,
Van Den Berg DJ,
Cortessis VK,
Smedby KE
and 55 more — show all
Glaser SL,
Westra HJ,
Robison LL,
Mack TM,
Ghesquieres H,
Hwang AE,
Nieters A,
de Sanjose S,
Lightfoot T,
Becker N,
Maynadie M,
Foretova L,
Roman E,
Benavente Y,
Rand KA,
Nathwani BN,
Glimelius B,
Staines A,
Boffetta P,
Link BK,
Kiemeney L,
Ansell SM,
Bhatia S,
Strong LC,
Galan P,
Vatten L,
Habermann TM,
Duell EJ,
Lake A,
Veenstra RN,
Visser L,
Liu Y,
Urayama KY,
Montgomery D,
Gaborieau V,
Weiss LM,
Byrnes G,
Lathrop M,
Cocco P,
Best T,
Skol AD,
Adami HO,
Melbye M,
Cerhan JR,
Gallagher A,
Taylor GM,
Slager SL,
Brennan P,
Coetzee GA,
Conti DV,
Onel K,
Jarrett RF,
Hjalgrim H,
van den Berg A,
McKay JD
Nature communications · 2014 · PMID 24920014 · open access
Questions about rs2069757
What is rs2069757?
rs2069757 is a single position in the genome, in or near the IL13 gene. Published research associates it with hodgkin's lymphoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2069757 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2069757 come from?
GWAS Catalog, Nat Commun 2014, PMID:24920014. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants