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Angiotensin-converting enzyme inhibitor intolerance

RBFOX3 · rs2061538

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Angiotensin-converting enzyme inhibitor intolerance — no copies of the reported risk allele. (GWAS Catalog, Pharmacogenet Genomics 2017, PMID:28030426)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Angiotensin-converting enzyme inhibitor intolerance. (GWAS Catalog, Pharmacogenet Genomics 2017, PMID:28030426)
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Angiotensin-converting enzyme inhibitor intolerance compared to the general population. (GWAS Catalog, Pharmacogenet Genomics 2017, PMID:28030426)

Source: GWAS Catalog, Pharmacogenet Genomics 2017, PMID:28030426

Questions about rs2061538

What is rs2061538?

rs2061538 is a single position in the genome, in or near the RBFOX3 gene. Published research associates it with angiotensin-converting enzyme inhibitor intolerance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2061538 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2061538 come from?

GWAS Catalog, Pharmacogenet Genomics 2017, PMID:28030426. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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