Standard

Obesity (extreme)

TDH · rs2060457

Where this position leads

Condition: Obesity and Body Weight

rs2060457 Condition: Obesity and Body Weight Obesity and Body Weight Condition rs2060457 rs2060457 TDH

What the study found

Who was studied 984 cases, 2,012 controls.

The effect Each copy of the T allele carried 1.38 times the odds of Obesity (extreme) (95% confidence interval 1.27-1.49); p = 3 × 10−8.

How common The T allele had a frequency of about 49% in the people studied.

Where it sits Chromosome 8, band 8p23.1 — in an intron of TDH.

What each result means

C/C No copy of the version the research linked to Obesity (extreme). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Obesity (extreme). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Obesity (extreme). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2060457

What is rs2060457?

rs2060457 is a single position in the genome, in or near the TDH gene. Published research associates it with obesity (extreme). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2060457 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs2060457 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2060457 come from?

GWAS Catalog, G3 (Bethesda) 2019, PMID:31888951. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Obesity (extreme) (rs2060457). MyGeneLog™. https://www.mygenelog.com/variants/rs2060457

← See all variants