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Who was studied at least 185,000 European or East Asian ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples).
The effect
Each copy of the G allele shifted the measure 0.024 lower (95% confidence interval 0.017-0.031); p = 3 × 10−10.
Where it sits Chromosome 4, band 4q31.22 — between genes, 10.5 kb from MIR548G.
What each result means
A/ANo copy of the version the research linked to Coronary artery disease (MTAG). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Coronary artery disease (MTAG). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Coronary artery disease (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39537608 · open access
Questions about rs2059904
What is rs2059904?
rs2059904 is a single position in the genome, in or near the near MIR548G gene. Published research associates it with coronary artery disease (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2059904 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs2059904 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2059904 come from?
GWAS Catalog, Nature communications 2024, PMID:39537608. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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