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Prostate-specific antigen levels

SPRED1 · rs2056507

What the study found

Who was studied 61,745 African ancestry individuals, 6,967 Asian ancestry individuals, 297,166 European ancestry individuals, 26,644 Hispanic or Latin American individuals.

The effect Each copy of the A allele shifted the measure 0.0164 lower (95% confidence interval 0.011-0.021); p = 2 × 10−10.

Where it sits Chromosome 15, band 15q14 — in an intron of SPRED1.

What each result means

A/A Two copies of the version the research linked to Prostate-specific antigen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Prostate-specific antigen levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Prostate-specific antigen levels. This is the starting point the study compared everyone against.
Source

Questions about rs2056507

What is rs2056507?

rs2056507 is a single position in the genome, in or near the SPRED1 gene. Published research associates it with prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2056507 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2056507 come from?

GWAS Catalog, Nature genetics 2025, PMID:39930085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Prostate-specific antigen levels (rs2056507). MyGeneLog™. https://www.mygenelog.com/variants/rs2056507

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