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Who was studied 9,433 British ancestry cases, 318,237 British ancestry controls.
The effect
Each copy of the A allele carried 1.18 times the odds of Asthma (childhood onset) (95% confidence interval 1.137-1.214); p = 3 × 10−22.
How common The A allele had a frequency of about 25% in the people studied.
Where it sits Chromosome 5, band 5q31.1 — in an intron of KIF3A.
What each result means
A/ATwo copies of the version the research linked to Asthma (childhood onset). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Asthma (childhood onset). That is a smaller link than two copies.
C/CNo copy of the version the research linked to Asthma (childhood onset). This is the starting point the study compared everyone against.
The Lancet. Respiratory medicine · 2019 · PMID 31036433
Questions about rs2051809
What is rs2051809?
rs2051809 is a single position in the genome, in or near the KIF3A gene. Published research associates it with asthma (childhood onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2051809 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs2051809 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2051809 come from?
GWAS Catalog, The Lancet. Respiratory medicine 2019, PMID:31036433. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 121227Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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